The adverse drug reactions (ADRs) reported during invitro studies and controlled trials usually did not reflect the real safety profiles of drugs. Many ADRs reported after introduction of the drugs in real clinical practice. ADRs could be reported at hospitals by physicians or nurses and even the patients could report ADRs. Pharmacist as drugs expertise could play an important role in ADRs reporting. Community pharmacists in Sudan are contributing in the process of malaria treatment so this research was carried to assess the role of community pharmacists in reporting of antimalarials ADRs. The study was carried in Khartoum between June to December 2016. A total of 293 pharmacists participated in the study. Data was collected via structured pre tested self -administered questionnaire. Data was analyzed using SPSS version 23. It was noted that 92.2% of the respondents were between the age of 20-39 years and 63.8% were having less than 5 years of experience. About 17.7% of the total surveyed pharmacists never advised the patients about antimalarials ADRs however 38.6% reported that sometimes they do advice the patients. Only 23(7.8%) of the pharmacists reported ADRs before. About 13%of the ADRs cases were reported to the pharmacovigilance center and the majority (56.5%) reported to the treating medical doctor. Majority of the pharmacists reported lack of training and lack of feedback from the patients as barriers to effective ADRs reporting. Improving pharmacists ADRs reporting skills through training is required to improve the situation in Sudan.