Vector behavior change and human behavior limit the effectiveness of the primary measures to control mosquitoes both indoors and outdoors, and challenge our capacity to sustain malaria prevention programs at community levels. In this address, I explore the potential of civil society groups and small-scale enterprise as critical partners in disease control. I will argue that simple affordable interventions can be disseminated and distributed through community networks, and illustrate this by describing various models of social innovation and empowerment. The involvement of existing third sector institutions -- local associations, social and micro-enterprise, non-profits and co-operatives -- and small-scale enterprise, offers a sustainable alternative to state-based interventions. While disseminating prevention technologies, the involvement of community organisations strengthens the links between community members, health centres and control programs and encourages engagement in health governance in ways that strengthen community use of health facilities.