Abstract
Yunnan is situated in a mountainous province, elevation from 76.4m to 6,740m. There are six river systems and 4060km border with Vietnam, Laos and Myanmar. Yunnan were malaria endemicity with an annual incidence of 249.38/10,000 in 1953. Now malaria transmission has been interrupted, only 325 imported cases were detected in 2017. Used drugs, dihydroartemisinin-piperaquine for treatment of P. falciparum and chloroquine for treatment of P. vivax, are still efficacy. These achievements are largely attributed to flexible, feasible and effective interventions. “Three all strategies, i.e. all people take drugs for prevention, all people treated for radical cure, all houses sprayed with insecticide” were ever widely used in hyperendemic areas in early stage of malaria program in China. Then a more focal approach was used with decreasing malaria and prevalence. In elimination phase, three strategies were emphasized, i.e. Strategy 1 - all health facilities have to improve case-based surveillance and response system; strategy 2 - intensive interventions on the first line along common border and Strategy 3 - friendly collaboration with three neighboring countries. From 2007 to 2013, cross burden collaboration reduced malaria burden by 89% in five special regions of Myanmar, which contributed to malaria elimination in China. In delivery of interventions, the strong governmental commitment, social mobilization and community engagement promoted coverage of interventions and peoples’ compliance.This case suggests that two issues (which strategies is more effective? what kind of treatment may cause drug resistance?) are deserved to be considered carefully
Key Words: Border Malaria elimination; Drug resistance; Strategy; China