Among the regions that remain endemic for malaria, the Americas has demonstrated the greatest potential for malaria elimination given its current malaria burden and expression of strong commitment by stakeholders including the national governments. Instrumental to the region’s reinforced efforts to eliminate the disease is the documentation, promotion, and replication of malaria best practices and lessons learned from programs and efforts implemented in various countries and frontline communities, accomplished through the Region’s annual search for the Malaria Champions of the Americas. Since 2009, twenty-seven champions have been recognized from Brazil, Colombia, Costa Rica, Dominican Republic, Ecuador, El Salvador, Guatemala, Haiti, Honduras, Mexico, Nicaragua, Paraguay, and Suriname. The Malaria Champions of the Americas is a collaborative program of the Pan American Health Organization / World Health Organization (PAHO/WHO) in partnership with the United Nations Foundation (UN Foundation), the George Washington University Milken Institute School of Public Health (GWSPH), the John Hopkins Bloomberg School of Public Health’s Center for Communication Programs (JHU-CCP), the Global Health Consortium at the Stempel College of Public Health & Social Work, Florida International University (FIU-GHC), and the American Society of Tropical Medicine and Hygiene (ASTMH).